If you use your Android phone or tablet for work, you might want to check in with your IT department before you install the software. If you're lucky, they've been using the Developer Preview and they'll be able to provide you with advice.
Enterprise Android problems are extremely common, particularly after major system updates like Android 6.0 Marshmallow. Your IT department could warn you about potential problems and give you guidence as far as timing. Maybe you need to wait a few days for additional testing.
If you don't have an IT department, you might want to think about checking in with a knowledgeable co-worker that already has Android Marshmallow on board their Nexus. Pick their brain and ask about the update's performance with any enterprise services you might be using.