When and if you decide to install the iOS 10.3.3 beta, make sure you set aside some free time at home base to make the download happen.
The iOS 10.3.3 beta isn't huge but you'll want to block off at least 20 minutes of free time to ensure that the download and installation process goes smoothly. Longer if this is going to be your first attempt at a beta.
On top of that, you'll also want to keep a close eye on performance after you get the iOS 10.3.3 beta on board your device. Problems are common on early software so you'll want to survey to make sure everything checks out.
You probably don't want to install this at work. If you install the update at home you'll be near your backups, you'll be on a secure network, and you'll be in a place where you can handle any problems the iOS 10.3.3 beta throws your way.